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Breakthroughs in Action 2025

In 2025 we funded the following research:

Maria Basil, MD, PhD

Uncovering Clonal Epithelial Dysregulation in Lung Cancer and Associated Risk Factors

Meghan Logun, PhD:

Novel Porcine Brain-Derived Hydrogel Carrier for Intratumoral Administration of CAR T Cells in Post-Resection GB

Ahmed Diab, PhD

Ex Vivo Tumor Slice Cultures to Develop Targeted Therapy Combinations that Potentiate Immunotherapy Responses in HPV+ Head and Neck Cancers

Roger Kim, MD, PhD

Examining Clinician Perceptions of Pulmonary Nodule Risk Stratification ToolsAndrew Zahrt, PhD

Automation and Machine-Learning-Driven Exploration of Linker-Space for PROTAC Optimization

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Breakthrough Challenge 14 W. Highland AveĀ  Philadelphia, PA 19118

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