The Breakthrough Challenge
We raise funds to support breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center (ACC). Founded in 2013, the Breakthrough Challenge unites patients, researchers, their families, and friends for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley. To date, the Breakthrough Challenge has donated over $3.1 million dollars to the ACC, funding 74 research projects. 100% of all participant-raised dollars are donated directly to cancer research.
Our 2026 Fundraising Goal
$71,924
Raised of $300,000
Meet the Match Challenge Has Begun!
(as of July 6th, 2026 12:00 AM until funding is exhausted)
Don't miss your chance to make 2x the impact!
The first $50,000 in donations received will be matched, dollar for dollar. Share your fundraising page uvdollar brings us closer to breakthrough cures!
With your help, we can continue to fund groundbreaking cancer research at Penn Medicine's Abramson Cancer Center.
$6,144 funds remaining as of July 14th, 8:00 AM
Thank You to Our Match Challenge Partner
Our 2025 Event Raised $350K!
Our Leaderboards
Top Fundraisers
Top Individuals (154)
View AllDavid Wellborn
$7,350.00 raised of $15,000.00
Bo Ebby
$5,850.00 raised of $15,000.00
Bruce Levine
$3,250.00 raised of $30,000.00
Christopher Hall
$2,750.00 raised of $1,000.00
Top Teams (21)
View AllKeystone State Ride
$30,610.00 raised of $60,000.00
Team BC
$8,276.00 raised of $25,000.00
Team Krieger
$5,350.00 raised of $20,000.00
CARs Pedaling For Cures
$5,050.00 raised of $30,000.00
Team Zayde
$4,572.00 raised of $18,000.00
Donate To an Indvidual or a Team
Donate NowBreakthroughs in Action
Join Us to Make a Difference!
